What does the Claus model for breast cancer risk assess?

What does the Claus model for breast cancer risk assess?

• A. Environmental exposure to toxins
• B. Number of first- and second-degree relatives with breast cancer
• C. Genetic markers for breast cancer
• D. Age at first menstruation

Answer: (B)

The Claus model for breast cancer risk is primarily focused on genetic factors, specifically the family history of breast cancer. This model evaluates the number of first-degree relatives (such as mothers and sisters) and second-degree relatives (like grandmothers and aunts) who have had breast cancer to determine an individual's risk. The rationale behind this approach is that breast cancer can have a hereditary component, and having multiple family members diagnosed with the disease increases the likelihood of a genetic predisposition. While other factors, like environmental exposure or genetic markers, can contribute to breast cancer risk, the Claus model specifically quantifies risk based on familial connections. This makes it a valuable tool in identifying individuals who may benefit from increased surveillance or preventive measures due to family history. Age at first menstruation, while potentially relevant to breast cancer risk, is not a component of the Claus model's assessment.

The Claus model for breast cancer risk is primarily focused on genetic factors, specifically the family history of breast cancer. This model evaluates the number of first-degree relatives (such as mothers and sisters) and second-degree relatives (like grandmothers and aunts) who have had breast cancer to determine an individual's risk. The rationale behind this approach is that breast cancer can have a hereditary component, and having multiple family members diagnosed with the disease increases the likelihood of a genetic predisposition.

While other factors, like environmental exposure or genetic markers, can contribute to breast cancer risk, the Claus model specifically quantifies risk based on familial connections. This makes it a valuable tool in identifying individuals who may benefit from increased surveillance or preventive measures due to family history. Age at first menstruation, while potentially relevant to breast cancer risk, is not a component of the Claus model's assessment.